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  • DHSC gives go ahead for boys to receive HPV vaccine

    DHSC gives go ahead for boys to receive HPV vaccine

    Friday, 27 July 2018 16:22
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    Friday, 27 July 2018 16:16
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    Thursday, 26 July 2018 15:29
  • Pharmacy bodies welcome Health Secretary’s pledge to invest in community pharmacy

    Pharmacy bodies welcome Health Secretary’s pledge to invest in community pharmacy

    Tuesday, 24 July 2018 13:07

a woman taking a pillFebruary 16 2018

New guidance has been issued advising about contraceptive options for women taking drugs linked to teratogenicity, or if a male partner is.

The statement by the Faculty of Sexual and Reproductive Healthcare applies to known teratogenic drugs or drugs with potential teratogenic effects. Women taking these medicines (or whose partner is), “should always be advised to use highly effective contraception both during treatment and for the recommended timeframe after discontinuation to avoid unintended pregnancy.”

Details of drugs associated with teratogenicity are listed on the UKTIS (UK Teratology Information Service) website.

The FSRH statement warns: “Advice given in the Summaries of Product Characteristics (SPC) regarding the use of contraception is not consistent for different teratogenic drugs. In some instances, ‘effective contraception’ is recommended. In others, use of ‘two methods of effective contraception’ is advised. Sometimes no advice is given. It is unclear which methods of contraception are considered ‘effective’ or why use of more than one method is sometimes advised.”

Recommendations about advice for women, if they or their male partner is using a teratogenic drug, are to make the patient aware that:

  • no method of contraception is 100% effective;
  • contraception methods considered ‘highly effective’ include the long-acting reversible contraceptives (LARC) copper intrauterine device (Cu-IUD), levonorgestrel intrauterine system (LNG-IUS) and progestogen-only implant (IMP) and male and female sterilisation, all of which have a failure rate of less than 1% with typical use;
  • additional contraceptive precautions (eg condoms or a second effective contraceptive method) are not required if a Cu-IUD, LNG-IUS, IMP or male or female sterilisation is being used;
  • women using hormonal contraception should use additional contraceptive precautions (eg condoms) due to potential failure rates as high as 9% with the oral pill, and 6% with the depot injection of medroxyprogesterone acetate (DMPA);
  • barrier methods, withdrawal or fertility awareness methods used on their own are recommended.

Links:
FSRH announcement    
FSRH CEU ‘Contraception for women using known teratogenic drugs or drugs with potential teratogenic effects’. February 2018.             
UKTIS website   

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